Home > Product > Antibody > Rabbit Anti-UQCRC2/FITC Conjugated antibody
Ubiquinol cytochrome c reductase complex core protein 2 mitochondrial; Ubiquinol cytochrome c reductase core protein II; UQCRC2; EC 1.10.2.2.
Cat:
SL3973R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human UQCRC2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
48kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.

Function:
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.

Subunit:
The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).

Subcellular Location:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Similarity:
Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.

Database links:

Entrez Gene: 7385 Human

Entrez Gene: 67003 Mouse

Entrez Gene: 293448 Rat

Omim: 191329 Human

SwissProt: P23004 Cow

SwissProt: P22695 Human

SwissProt: Q9DB77 Mouse

SwissProt: P32551 Rat

Unigene: 521763 Human

Unigene: 334206 Mouse

Unigene: 2334 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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