Home
>
Product
>
Antibody
>
Rabbit Anti-NDUFA8/FITC Conjugated antibody
background:
NDUFA8 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subunit:
Complex I is composed of 45 different subunits.
Subcellular Location:
Mitochondrion. Mitochondrion intermembrane space.
Post-translational modifications:
May contain intrachain disulfide bonds, as evidenced by its electrophoretic mobility under reducing vs non-reducing conditions.
Similarity:
Belongs to the complex I NDUFA8 subunit family.
Contains 2 CHCH domains.
Database links:
Entrez Gene: 4702 Human
Entrez Gene: 68375 Mouse
Omim: 603359 Human
SwissProt: P51970 Human
SwissProt: Q9DCJ5 Mouse
Unigene: 495039 Human
Unigene: 19834 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|