Rabbit Anti-APOA4/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-APOA4/FITC Conjugated antibody

Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156.

Cat:

SL3876R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Dog,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human APOA4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

44kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties

Function:
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoSLCII; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.

Subcellular Location:
Secreted.

Tissue Specificity:
Synthesized primarily in the intestine and secreted in plasma.

Post-translational modifications:
Phosphorylation sites are present in the extracellular medium.

Similarity:
Belongs to the apolipoprotein A1/A4/E family.

Database links:

Entrez Gene: 337 Human

Omim: 107690 Human

SwissProt: P06727 Human

Unigene: 1247 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall