Home
>
Product
>
Antibody
>
Rabbit Anti-Apg12/FITC Conjugated antibody
background:
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998[PubMed 9852036]).[supplied by OMIM].
Function:
Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the ATG12 family.
Database links:
Entrez Gene: 9140 Human
Entrez Gene: 67526 Mouse
Entrez Gene: 361321 Rat
Omim: 609608 Human
SwissProt: O94817 Human
SwissProt: Q9CQY1 Mouse
SwissProt: Q2TBJ5 Rat
Unigene: 264482 Human
Unigene: 9852 Mouse
Unigene: 6224 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|