Home > Product > Antibody > Rabbit Anti-Apg12/FITC Conjugated antibody
APG12-like; APG12L; ATG12; ATG12 autophagy related 12 homolog; Autophagy 12; Autophagy-related protein 12; HAPG12; Ubiquitin-like protein ATG12; ATG12_HUMAN.
Cat:
SL4012R-FITC
Species Reactivity:
Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human Apg12
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
15/21kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998[PubMed 9852036]).[supplied by OMIM].

Function:
Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the ATG12 family.

Database links:

Entrez Gene: 9140 Human

Entrez Gene: 67526 Mouse

Entrez Gene: 361321 Rat

Omim: 609608 Human

SwissProt: O94817 Human

SwissProt: Q9CQY1 Mouse

SwissProt: Q2TBJ5 Rat

Unigene: 264482 Human

Unigene: 9852 Mouse

Unigene: 6224 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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