Rabbit Anti-Integrin alpha 4+Beta 7/FITC Conjugated antibody

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Alpha 4 subunit of VLA 4 receptor; Antigen CD49D; CD 49d; CD49d; CD49d antigen; IA 4; IA4; Integrin alpha 4; Integrin alpha 4 subunit; Integrin alpha IV; Integrin beta 7; Integrin beta 7 subunit; ITGA 4; ITGA4; ITGA4 protein; ITGB 7; ITGB7

Cat:

SL2055R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Integrin alpha 4+Beta 7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

114kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.

Subcellular Location:
Membrane; Single pass type I membrane protein.

Database links:

Entrez Gene: 3676 Human

Entrez Gene: 11281 Mouse

Omim: 192975 Human

SwissProt: P13612 Human

SwissProt: Q00651 Mouse

Unigene: 88955 Human

Unigene: 31903 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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