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Home > Product > Antibody > Rabbit Anti-Phospholipase A2 activator protein/FITC Conjugated antibody
Glycerophosphatase; Phospholipase A 2 activating protein; Phospholipase A2 activating protein; PLA2P; PLAA; PLAP.
Cat:
SL3807R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
87kDa
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Price: $
Product PDFs
Datasheet:


background:
Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha.

Database links:

Entrez Gene: 9373 Human

Omim: 603873 Human

SwissProt: Q9Y263 Human

Unigene: 27182 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

磷脂酶A2激活蛋白能激活磷脂酶A2，是类花生酸形成的一个重要中介体。作为促炎症反应剂，PLAP存在于类风湿性关节炎患者的炎症组织和滑膜液，因而被认为在炎症性疾病调控中发挥重要作用。IL-1β和TNF-α能刺激PLAP的形成。PLAP作为睾丸精原细胞瘤的标志物。
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