Rabbit Anti-ANO1/TMEM16A/FITC Conjugated antibody

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ANO 1; ANO1; ANO1_HUMAN; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Anoctamin-1; Anoctamin1; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; FLJ10261; Membrane protein; Oral cancer overexpressed 2; Oral cancer overexpress

Cat:

SL3794R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human DOG-1/TMEM16A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

114kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development.

Function:
Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm.

Tissue Specificity:
Broadly expressed with higher levels in liver and skeletal muscle.

Similarity:
Belongs to the anoctamin family.

Database links:

Entrez Gene: 55107 Human

Entrez Gene: 101772 Mouse

Entrez Gene: 309135 Rat

Omim: 610108 Human

SwissProt: Q5XXA6 Human

SwissProt: Q8SHY3 Mouse

Unigene: 503074 Human

Unigene: 26700 Mouse

Unigene: 162509 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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