Home
>
Product
>
Antibody
>
Rabbit Anti-S100A4/FITC Conjugated antibody
background:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Subunit:
Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the S-100 family.
Contains 2 EF-hand domains.
Database links:
Entrez Gene: 282343 Cow
Entrez Gene: 403787 Dog
Entrez Gene: 6275 Human
Entrez Gene: 20198 Mouse
Entrez Gene: 24615 Rat
Omim: 114210 Human
SwissProt: P35466 Cow
SwissProt: Q9TV56 Dog
SwissProt: P26447 Human
SwissProt: P07091 Mouse
SwissProt: P05942 Rat
Unigene: 654444 Human
Unigene: 3925 Mouse
Unigene: 504 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|