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Rabbit Anti-GPR15/FITC Conjugated antibody
background:
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]
Function:
Probable chemokine receptor. Alternative coreceptor with CD4 for HISLV1 infection.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
Entrez Gene: 2838 Human
Entrez Gene: 71223 Mouse
Entrez Gene: 288181 Rat
Omim: 601166 Human
SwissProt: P49685 Human
SwissProt: Q0VDU3 Mouse
Unigene: 563128 Human
Unigene: 359970 Mouse
Unigene: 426544 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体是一种细胞表面受体,能将细胞外的分子信号传递至细胞内激起细胞反应,对多种细胞行起调控作用。G蛋白偶联受体(GPCR)参与了机体内多种生理过程的调节,是目前治疗多种人类疾病包括代谢性疾病的药物靶点。
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