background:
SLC44A1 (Solute carrier family 44, member 1) is an intermediate-affinity, Na+-independent choline transporter. It is thought to be important for the production of the membrane lipid phosphatidylcholine. Hence, it may have a role in membrane synthesis and myelin production.
Function:
Choline transporter. May be involved in membrane synthesis and myelin production.
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in various cells of the hematopoietic system.
Similarity:
Belongs to the CTL (choline transporter-like) family.
Database links:
Entrez Gene: 23446 Human
Entrez Gene: 100434 Mouse
Entrez Gene: 85254 Rat
Omim: 606105 Human
SwissProt: Q8WWI5 Human
SwissProt: Q6X893 Mouse
SwissProt: Q8VII6 Rat
Unigene: 573495 Human
Unigene: 482207 Mouse
Unigene: 482289 Mouse
Unigene: 97686 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SLC44A1蛋白又称胆碱转运体样蛋白1,
是与钠离子无关的胆碱酯酶转运,该蛋白与磷脂脂质膜的维系增值相关联,在髓鞘膜合成和生产中发挥着作用。
|
|