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Rabbit Anti-KCNC4/FITC Conjugated antibody
background:
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010].
Subunit:
Homotetramer (Probable). Heterotetramer of potassium channel proteins.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.4/KCNC4 sub-subfamily.
Database links:
Entrez Gene: 3749 Human
Entrez Gene: 99738 Mouse
Entrez Gene: 684516 Rat
Omim: 176265 Human
SwissProt: Q03721 Human
SwissProt: Q8R1C0 Mouse
SwissProt: Q63734 Rat
Unigene: 153521 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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