Home > Product > Antibody > Rabbit Anti-CD134/FITC Conjugated antibody
Tumor necrosis factor receptor superfamily member 4; ACT 35; ACT35; ACT35 antigen; CD 134; CD134 antigen; Lymphoid activation antigene ACT35; OX 40; OX40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally activ
Cat:
SL2685R-FITC
Species Reactivity:
Human,Mouse,Rat,(predicted: Dog,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human TNFRSF4 (101-160aa)
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
27kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008].

Function:
Receptor for TNFSF4/OX40L/GP34.

Subunit:
Interacts with TRAF2, TRAF3 and TRAF5.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 4 TNFR-Cys repeats.

Database links:

Entrez Gene: 7293 Human

Omim: 600315 Human

SwissProt: P43489 Human

Unigene: 129780 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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