Rabbit Anti-MARCO/FITC Conjugated antibody

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Macrophage receptor MARCO; Marco; MARCO_HUMAN; Macrophage receptor with collagenous structure; SCARA2; Scavenger receptor class A member 2.

Cat:

SL2659R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Chicken,Dog,Guinea Pig,,G)

Immunogen：

KLH conjugated synthetic peptide derived from human MARCO

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

53kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, SLCterminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq].

Function:
Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria.

Subunit:
Homotrimer. Trimers may assemble in larger oligomers thus resulting in the creation of a large surface capable of interacting with very large ligands.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Contains 1 collagen-like domain.
Contains 1 SRCR domain.

Database links:

Entrez Gene: 8685 Human

Omim: 604870 Human

SwissProt: Q9UEW3 Human

Unigene: 67726 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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