Home
>
Product
>
Antibody
>
Rabbit Anti-LIR-6/LILRA1/FITC Conjugated antibody
background:
This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Function:
May act as receptor for class I MHC antigens.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Detected in monocytes and B-cells.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
Database links:
Entrez Gene: 11024 Human
Omim: 604810 Human
SwissProt: O75019 Human
Unigene: 710507 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|