Rabbit Anti-LTB4-R2/FITC Conjugated antibody

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BLT2R; JULF2; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LT4R2_HUMAN; LTB4 receptor JULF2; LTB4-R 2; LTB4-R2; LTB4R2; Seven transmembrane receptor BLTR2.

Cat:

SL2655R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human LTB4-R2 N-terminus

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

41kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Function:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 56413 Human

Entrez Gene: 57260 Mouse

Omim: 605773 Human

SwissProt: Q9NPC1 Human

SwissProt: Q9JJL9 Mouse

Unigene: 642693 Human

Unigene: 657595 Human

Unigene: 159670 Mouse

Unigene: 485286 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白三烯B4受体2是白三烯B4受体的新亚型，在炎症、免疫系统疾病和变态反应、包括一些肿瘤中发挥着重要作用。

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