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Rabbit Anti-KIR2DS4/CD158i/FITC Conjugated antibody
background:
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells.
Function:
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Database links:
Entrez Gene: 3809 Human
Omim: 604955 Human
SwissProt: P43632 Human
Unigene: 65928 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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