Rabbit Anti-IL22/FITC Conjugated antibody

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Interleukin-22; Il22; IL-22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23;

Cat:

SL2623R-FITC

Species Reactivity：

Human,Mouse,(predicted: Rat,Dog,)

Immunogen：

KLH conjugated synthetic peptide derived from human IL-22

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].

Function:
Cytokine that contributes to the inflammatory response in vivo.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-10 family.

Database links:

Entrez Gene: 50616 Human

Entrez Gene: 50929 Mouse

Entrez Gene: 500836 Rat

Omim: 605330 Human

SwissProt: Q9GZX6 Human

SwissProt: Q9JJY9 Mouse

Unigene: 287369 Human

Unigene: 103585 Mouse

Unigene: 195879 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IL-22是白介素-10家族的成员,主要是由激活的T 淋巴细胞产生的一类重要的细胞因子,除了在Th17细胞中高表达之外，在NK和NKT等细胞中也有表达,在组织损伤修复以及牛皮癣、肝炎、肺炎、肠炎等慢性炎症中发挥重要作用.IL-22是继IL-6和IL-10之后又一个参与炎症反应和代谢调控的细胞因子，IL-22有可能成为干预脂肪肝发生发展的新方法。

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