Rabbit Anti-IL3/FITC Conjugated antibody

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Burst promoting activity; Colony stimulating factor multiple; Eosinophil colony stimulating factor; Hematopoietic growth factor; IL-3; IL3; IL3_MOUSE; Interleukin 3 (colony stimulating factor, multiple); IL 3; Interleukin 3; Mast cell growth factor; MCGF;

Cat:

SL2598R-FITC

Species Reactivity：

(predicted: Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from mouse IL-3 (112-140aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

16kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The pleiotropic IL3 (Interleukin 3) is a 15kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.

Function:
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Tissue Specificity:
Activated T-cells, mast cells, natural killer cells.

Similarity:
Belongs to the IL-3 family.

Database links:

Entrez Gene: 3562 Human

Omim: 147740 Human

SwissProt: P08700 Human

Unigene: 694 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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