Home > Product > Antibody > Rabbit Anti-CXCL5/FITC Conjugated antibody
AMCFII; C-X-C motif chemokine 5; Cxcl5; CXCL5_HUMAN; ENA-78(1-78); ENA-78(9-78); ENA78; Epithelial derived neutrophil activating peptide 78; Epithelial derived neutrophil activating protein 78; Epithelial-derived neutrophil-activating protein 78; GCP2; LI
Cat:
SL2549R-FITC
Species Reactivity:
Rat,(predicted: Mouse,)
Immunogen:
KLH conjugated synthetic peptide derived from mouse CXCL5
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
8/9kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. [provided by RefSeq].

Function:
May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.

Subcellular Location:
Secreted.

Post-translational modifications:
GCP-2(1-78) and GCP-2(9-78) are produced by proteolytic cleavage after secretion from fibroblasts and epithelial cells. GCP-2(9-78) is the most prominent form. A number of additional N-terminal (processed between pos. 41 and 48) and SLCterminal (processed between pos. 118 and 132) processed forms have been identified, probably also representing intermediate states.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

Database links:

Entrez Gene: 6374 Human

Entrez Gene: 20311 Mouse

Omim: 600324 Human

SwissProt: P42830 Human

SwissProt: P50228 Mouse

Unigene: 89714 Human

Unigene: 4660 Mouse




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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