Rabbit Anti-ALT1/FITC Conjugated antibody

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Alanine aminotransferase; AAT 1; AAT1; Alanine aminotransferase 1; alanine aminotransferase; ALT 1; ALT1; Glutamic alanine transaminase 1; Glutamic pyruvate transaminase; Glutamic pyruvic transaminase 1; Glutamic-alanine transaminase; GPT 1; GPT; GPT1; SG

Cat:

SL2532R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human ALT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

55kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Alanine Transaminase [glutamic pyruvate transaminase - GPT] participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Pyridoxal phosphate is a known cofactor. Expression is induced by glucocorticoids. This enzyme is present in a high concentration in liver tissue and it's release into the blood indicates liver disease or damage.

Function:
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue.

Similarity:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

Database links:

Entrez Gene: 539188 Cow

Entrez Gene: 2875 Human

Entrez Gene: 76282 Mouse

Entrez Gene: 81670 Rat

Omim: 138200 Human

SwissProt: A4IFH5 Cow

SwissProt: P24298 Human

SwissProt: Q8QZR5 Mouse

SwissProt: P25409 Rat

Unigene: 103502 Human

Unigene: 30130 Mouse

Unigene: 6318 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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