Rabbit Anti-CD69/FITC Conjugated antibody

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CLEC2C; AIM; Early activation antigen CD69; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3; EA1; BL-AC/P26;C-type lectin domain family 2 member C.

Cat:

SL2499R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,)

Immunogen：

KLH conjugated synthetic peptide derived from human CD69

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

22kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]

Function:
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

Post-translational modifications:
Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

Similarity:
Contains 1 SLCtype lectin domain.

Database links:

Entrez Gene: 969 Human

Entrez Gene: 12515 Mouse

Entrez Gene: 29187 Rat

Omim: 107273 Human

SwissProt: Q07108 Human

SwissProt: P37217 Mouse

Unigene: 208854 Human

Unigene: 74745 Mouse

Unigene: 23779 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD69属于SLC型凝集素受体家族,也是NK细胞信号传导基因复合体家族的一员,是一种Ⅱ型跨膜糖蛋白.

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