Home > Product > Antibody > Rabbit Anti-CCL3/FITC Conjugated antibody
Tonsillar lymphocyte LD78 alpha protein; CCL 3; CCL3; Chemokine C C motif ligand 3; Chemokine CC Motif Ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein antibody L2G25B; LD78ALPHA; Macrophage inf
Cat:
SL2452R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from mouse CCL3
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
7.9kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]

Function:
Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in lung, spleen, and pancreas.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

Database links:

Entrez Gene: 6348 Human

Entrez Gene: 20302 Mouse

Entrez Gene: 25542 Rat

Omim: 182283 Human

SwissProt: P10147 Human

SwissProt: P10855 Mouse

SwissProt: P50229 Rat

Unigene: 514107 Human

Unigene: 1282 Mouse

Unigene: 10139 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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