Rabbit Anti-BDKRB2/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-BDKRB2/FITC Conjugated antibody

B2; B2 bradykinin receptor; B2BKR; B2BRA; B2R; BDKR B2; BDKRB 2; Bdkrb2; BK 2; BK 2 receptor; BK R2; BK2; BK2 receptor; BK2R; BKR 2; BKR2; BR B2; Bradykinin receptor b2; Bradykinin receptor beta 2; BRB 2; BRB2; DKFZp686O088; Kinin B2 Bradykinin receptor b

Cat:

SL2422R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human Bdkrb2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

43kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Bradykinin increases vascular permeability, dilates blood vessels, contracts non-vascular smooth muscle, and causes pain. This product detects a receptor for bradykinin. The receptor is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung,prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.

Function:
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Subunit:
Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.

Database links:

Entrez Gene: 624 Human

Entrez Gene: 12062 Mouse

Omim: 113503 Human

SwissProt: P30411 Human

SwissProt: P32299 Mouse

Unigene: 654542 Human

Unigene: 726620 Human

Unigene: 390475 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

缓激肽B2受体目前主要在糖尿病肾病的发生、发展中起着重要作用。

Product Feedback Wall