Rabbit Anti-IL-20R alpha/FITC Conjugated antibody

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Interleukin-20 receptor alpha chain precursor;IL-20RA; IL20 RA; IL-20 RA; E230031K19; FLJ40993; IL-20R1; IL20RA; ZCYTOR7;Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor family 2 member 8; CRF2

Cat:

SL2619R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human IL-20RA

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

59kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis. [provided by RefSeq]

Function:
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.

Subunit:
Heterodimer with IL20RB and heterodimer with IL10RB.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.

Similarity:
Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains.

Database links:

Entrez Gene: 53832 Human

Entrez Gene: 237313 Mouse

Omim: 605620 Human

SwissProt: Q9UHF4 Human

SwissProt: Q6PHB0 Mouse

Unigene: 445868 Human

Unigene: 234667 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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