Rabbit Anti-TGF beta Receptor III/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-TGF beta Receptor III/FITC Conjugated antibody

Beta glycan; TGF Beta R3; Betaglycan; Betaglycan proteoglycan; BGCAN; TGF beta receptor type 3; TGF-beta receptor type 3; TGF beta receptor type III; TGF-beta receptor type III; TGFB R3; TGFBR 3; TGFBR3; TGFR 3; TGFR-3; TGFR3; Transforming Growth Factor B

Cat:

SL1910R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TGFBR3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

94kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010].

Function:
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.

Subunit:
Interacts with TCTEX1D4.

Subcellular Location:
Secreted. Secreted > extracellular space. Cell membrane. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.

Post-translational modifications:
Extensively modified by glycosaminoglycan groups (GAG).

Similarity:
Contains 1 ZP domain.

Database links:

Entrez Gene: 7049 Human

Entrez Gene: 21814 Mouse

Omim: 600742 Human

SwissProt: Q03167 Human

SwissProt: O88393 Mouse

Unigene: 482390 Human

Unigene: 200775 Mous

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

转化生长因子β受体Ⅲ，TGFβRⅢ

Product Feedback Wall