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Rabbit Anti-RELM alpha/FITC Conjugated antibody
background:
A family of resistin-like molecules (RELMs) has been identified in rodents and humans. RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM alpha and RELM beta are 85-94 amino acid secreted proteins sharing a conserved SLCterminal domain. RELM alpha and Resistin are secreted exclusively by adipocytes while RELM beta is expressed in the epithelium of the colon and small bowel. The RELMs together with resistin comprise a class of tissue-specific signaling molecules. The physiological role and molecular targets of RELM alpha are still unknown.
Function:
Probable hormone. Plays a role in pulmonary vascular remodeling.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Tissue Specificity:
Highest levels in adipose tissue.
Similarity:
Belongs to the resistin/FIZZ family.
Database links:
Entrez Gene: 57262 Mouse
SwissProt: Q9EP95 Mouse
Unigene: 441868 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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