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Rabbit Anti-IL-20/FITC Conjugated antibody
background:
IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Function:
Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed at very low levels in skin, trachea, and other tissues.
Similarity:
Belongs to the IL-10 family.
Database links:
Entrez Gene: 50604 Human
Entrez Gene: 58181 Mouse
Omim: 605619 Human
SwissProt: Q9NYY1 Human
Unigene: 272373 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白介素20是新发现的细胞因子,属于白介素10家族成员。它可由活化的外周血单一核细胞和角质形成细胞产生。与其他白介素10家族成员的受体亚单位有交叉反应,多用于银屑病及风湿病的研究。
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