Rabbit Anti-Inhibin Beta C/FITC Conjugated antibody

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ACTIVIN BETA C; IHBC; INHBC; MGC108687; activin beta-C chain; Inhibin, beta C; inhibin beta C chain precursor; Inhbc; INHBC_HUMAN.

Cat:

SL1826R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human Inhibin Beta C

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

12.5kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.

Function:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subunit:
Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in benign prostatic hyperplasia.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 3626 Human

Entrez Gene: 64549 Rat

Omim: 601233 Human

SwissProt: P55103 Human

SwissProt: Q9WUK5 Rat

Unigene: 632722 Human

Unigene: 48697 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抑制素是转化生长因子TGFβ超级家族，主要由雌性动物卵巢颗粒细胞和雄性动物睾丸的Sertoli细胞分泌.研究表明,抑制素具有内分泌和旁分泌物的作用:既可通过复杂的反馈机理,调节体液FSH水平。

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