Rabbit Anti-Inhibin beta B/FITC Conjugated antibody

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MGC157939; Activin A; Activin AB alpha polypeptide; Activin AB; Activin AB beta polypeptide; Activin B; Activin beta A chain; Activin beta B chain; ActivinA; ActivinAB; ActivinB; EDF; Erythroid differentiation protein; follicle stimulating hormone releasi

Cat:

SL1825R-FITC

Species Reactivity：

Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human Inhibin beta B

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

13/45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq].

Subcellular Location:
Secreted.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 3625 Human

Entrez Gene: 16324 Mouse

Entrez Gene: 25196 Rat

Omim: 147390 Human

SwissProt: P09529 Human

SwissProt: Q04999 Mouse

SwissProt: P17491 Rat

Unigene: 1735 Human

Unigene: 3092 Mouse

Unigene: 35074 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抑制素是转化生长因子TGFβ超级家族，主要由雌性动物卵巢颗粒细胞和雄性动物睾丸的Sertoli细胞分泌.研究表明,抑制素具有内分泌和旁分泌物的作用:既可通过复杂的反馈机理,调节体液FSH水平。

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