Rabbit Anti-LDHA/FITC Conjugated antibody

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Lactate Dehydrogenase; Lactate Dehydrogenase Isoenzyme V; Lactate Dehydrogenase isozyme H4; L lactate dehydrogenase A chain; Lactate dehydrogenase A; Lactate dehydrogenase A chain; LDH A; LDH heart subunit; LDH M; LDHM; LDH muscle subunit; LDH1; LDHA; PIG

Cat:

SL1810R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human LDHA

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

37kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq].

Subunit:
Homotetramer.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
ISGylated.

DISEASE:
Glycogen storage disease 11 (GSD11) [MIM:612933]: A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the LDH/MDH superfamily. LDH family.

Database links:

Entrez Gene: 3939 Human

Entrez Gene: 16828 Mouse

Entrez Gene: 24533 Rat

Omim: 30000 Human

SwissProt: P00338 Human

SwissProt: P06151 Mouse

SwissProt: P04642 Rat

Unigene: 2795 Human

Unigene: 29324 Mouse

Unigene: 107896 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

乳酸脱氢酶(LD)广泛存在于人体各组织中，以肝、肾、心肌、骨骼肌、胰腺和肺中最多。

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