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Rabbit Anti-GPR78/FITC Conjugated antibody
background:
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
Function:
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
Entrez Gene: 27201 Human
Omim: 606921 Human
SwissProt: Q96P69 Human
Unigene: 350588 Human
Unigene: 740355 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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