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Rabbit Anti-HFH4/FITC Conjugated antibody
background:
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]
Function:
May play an important role in cell fate determination during lung development and in spermatogenesis.
Subcellular Location:
Nucleus.
Tissue Specificity:
Testis, oviduct, lung and brain cortex.
DISEASE:
Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Similarity:
Contains 1 fork-head DNA-binding domain.
Database links:
Entrez Gene: 2302 Human
Entrez Gene: 15223 Mouse
Entrez Gene: 116557 Rat
Omim: 602291 Human
SwissProt: Q92949 Human
SwissProt: Q61660 Mouse
SwissProt: Q63247 Rat
Unigene: 651204 Human
Unigene: 378938 Mouse
Unigene: 202954 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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