Rabbit Anti-Follistatin/FITC Conjugated antibody

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Activin binding protein; FS; Follistatin; Activin-binding protein; FS; fst; FST_HUMAN; Human follistatin gene; follistatin isoform FST344 precursor; FST344; follistatin isoform FST317 precursor; FST317; FST_HUMAN.

Cat:

SL1773R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Follistatin

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

38kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. There is evidence linking polycystic ovary syndrome and follistatin.
Follistatin binds directly to activin and functions as an activin antagonist. It specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone.

Subunit:
Monomer (Potential).

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.

Similarity:
Contains 3 follistatin-like domains.
Contains 3 Kazal-like domains.
Contains 1 TB (TGF-beta binding) domain.

Database links:

Entrez Gene: 396119 Chicken

Entrez Gene: 327681 Cow

Entrez Gene: 10468 Human

Entrez Gene: 14313 Mouse

Entrez Gene: 445002 Pig

Entrez Gene: 24373 Rat

Omim: 136470 Human

SwissProt: Q90844 Chicken

SwissProt: P50291 Cow

SwissProt: P19883 Human

SwissProt: P47931 Mouse

SwissProt: P10669 Pig

SwissProt: P21674 Rat

Unigene: 9914 Human

Unigene: 4913 Mouse

Unigene: 162557 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

促卵泡激素抑释素/卵泡抑素: 脑垂体细胞分泌的一种糖蛋白。可与促卵泡激素释放素/红细胞分化因子发生特异结合，抑制脑垂体分泌促卵泡激素。

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