Rabbit Anti-EGFL7/FITC Conjugated antibody

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EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGFL 7; Epidermal growth factor like domain protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple epidermal growth factor like domain protein

Cat:

SL1755R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from mouse EGFL7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

28kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Function:
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Subcellular Location:
Secreted (By similarity).

Tissue Specificity:
Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney.

Similarity:
Contains 2 EGF-like domains.
Contains 1 EMI domain.

Database links:

Entrez Gene: 51162 Human

Entrez Gene: 353156 Mouse

Omim: 608582 Human

SwissProt: Q9UHF1 Human

Unigene: 91481 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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