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Rabbit Anti-CA I/FITC Conjugated antibody
background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009]
Function:
Reversible hydration of carbon dioxide.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the alpha-carbonic anhydrase family.
Database links:
Entrez Gene: 759 Human
Entrez Gene: 12346 Mouse
Entrez Gene: 310218 Rat
Omim: 12960 Human
SwissProt: P00915 Human
SwissProt: P13634 Mouse
SwissProt: B0BNN3 Rat
Unigene: 23118 Human
Unigene: 273195 Mouse
Unigene: 6854 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CA1(Carbonic anhydrase1)是红细胞的主要蛋白质成分之一,是一种重要的锌酶,对血液及组织起到维持酸碱平衡的作用,协助体内组织排除二氧化碳,碳酸酐酶I参与呼吸、钙化、酸碱平衡、骨吸收和各种体液形成的生理过程。
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