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Rabbit Anti-CXCL16/FITC Conjugated antibody
background:
CXCL16 acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. It induces a strong chemotactic response and calcium mobilization. It binds to CXCR6/Bonzo.
Subcellular Location:
Cell membrane. Secreted. Also exists as a soluble form.
Tissue Specificity:
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.
Database links:
Entrez Gene: 58191 Human
Omim: 605398 Human
SwissProt: Q9H2A7 Human
Unigene: 513885 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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