background:
No data available.
Function:
Thrombin-like snake venom serine protease. Cleaves Arg-Gly bonds in fibrinogen alpha chains (FGA).
Subunit:
Secreted.
Subcellular Location:
Expressed by the venom gland.
Similarity:
Belongs to the peptidase S1 family. Snake venom subfamily.
Contains 1 peptidase S1 domain.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Batroxobin蛇毒巴曲酶蛋白是经生物工程提纯、精制而得丝氨酸蛋白酶。
其作用机制为:
①具有分解血纤维蛋白原、抑制血栓形成作用。
②具有诱发TPA的释放、增强TPA的作用、促进纤维蛋白溶酶的生成、减少α2-P1和PAI、溶解血栓的作用。
③具有降低血粘度、抑制红细胞凝集、沉降、增强红细胞的血管通过性及变形能力、降低血管阻力以及改善微循环等作用。使溶栓作用快速,缺血部位功能恢复,从而达到治疗和防止复发的效果。
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