background:
The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Belongs to the parvalbumin family. Contains 2 EF-hand domains. This protein binds two calcium ions.
Function:
In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
Similarity:
Belongs to the parvalbumin family.
Contains 2 EF-hand domains.
Database links:
Entrez Gene: 396459 Chicken
Entrez Gene: 396531 Chicken
Entrez Gene: 5816 Human
Entrez Gene: 19293 Mouse
Entrez Gene: 25269 Rat
Omim: 168890 Human
SwissProt: P20472 Human
SwissProt: P32848 Mouse
SwissProt: P02625 Rat
Unigene: 295449 Human
Unigene: 2766 Mouse
Unigene: 2005 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
(Parvalbumin, PV)细小白蛋白属于钙结合蛋白家族,是一种细胞内可溶的小结合蛋白,过去曾认为,仅出现在哺乳动物某些肌纤维内,它与Ca2+有高度亲合力,与钙调蛋白竞争自由Ca2+,故可阻止肌浆内的Ca2+增高,可抗衡细胞内钙过量的发生。
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