Rabbit Anti-APOH/FITC Conjugated antibody

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Apolipoprotein H; Activated protein C binding protein; APC inhibitor; APOH; B2G1; beta 2 glycoprotein I; beta 2 glycoprotein I precursor; BG; OTTMUSP00000003033; APOH_HUMAN.

Cat:

SL1570R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ApoH

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

36kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Apolipoprotein H is expressed by placental trophoblast cells at high levels. Although the normal physiological role is not known, the protein appears to act as a co-factor for the binding of autoantibodies to phospholipids to trophoblasts, which is a process involved in the pathogenesis of recurrent miscarriage.

Function:
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

Post-translational modifications:
N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.

Similarity:
Contains 4 Sushi (CCP/SCR) domains.

Database links:

Entrez Gene: 350 Human

Entrez Gene: 287774 Rat

Omim: 138700 Human

SwissProt: P02749 Human

SwissProt: P26644 Rat

Unigene: 445358 Human

Unigene: 1824 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

载脂蛋白H(apolipoprotein D,apoH)又称为β2糖蛋白Ⅰ(β2-glycoprotein,β2-GI)，是最初是在人血浆的高密度脂蛋白中被分离出来的。apoH在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。

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