background:
TRA16 may act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Function:
May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Subunit:
Interacts with NR2C2/TR4.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in all tissue examined, with highest expression in heart, skeletal muscle and pancreas.
Similarity:
Belongs to the NR2C2AP family.
Database links:
Entrez Gene: 126382 Human
Omim: 608719 Human
SwissProt: Q86WQ0 Human
Unigene: 708153 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
亚细胞定位于:细胞核 细胞浆。 主要表达在:肺、胸腺、睾丸
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