Rabbit Anti-SYAP1/FITC Conjugated antibody

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Synapse associated protein-1; synapse-associated protein 1-like; 2010110O17Rik, AW011796, DKFZp686K221, FLJ14495, FLJ44185, MGC94115, PRO3113, SYAP1; SYAP1_HUMAN; SAP-1.

Cat:

SL0121R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human SAP-1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

40kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SYAP1 (synapse-associated protein 1) is a 352 amino acid protein that is ubiquitously expressed in adult tissues. SYAP1 contains one BSD domain which is a novel domain that is present in basal transcription factors, synapse-associated proteins and several hypothetical proteins. The BSD domain is characterized by three predicted alpha helices and by conserved tryptophan and phenylalanine residues, located at the SLCterminus of the domain. The gene that encodes SYAP1 in humans is located on chromosome X. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Similarity:
Contains 1 BSD domain.

Database links:

Entrez Gene: 509355 Cow

Entrez Gene: 94056 Human

Entrez Gene: 67043 Mouse

Entrez Gene: 302678 Rat

SwissProt: Q96A49 Human

SwissProt: Q9D5V6 Mouse

Unigene: 729197 Human

Unigene: 44207 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

突触素SAP-1/SYP(Synaptophysin, FRG-4)是分布于突触囊泡膜上含量丰富的糖蛋白之一，与递质释放关系密切，并可影响突触可塑性。突触相关蛋白-1可作为神经元和神经内分泌细胞的可靠标记物用于神经系统形态、功能和发育以及相关疾病的研究。对于SAP-1的功能及其具体作用机制，尚待进一步研究。

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