Rabbit Anti-Maspin/FITC Conjugated antibody

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mammary serine proteinase inhibitor; Maspin; Ovalbumin; PI-5; PI5; Protease inhibitor 5; Serine (or cysteine) peptidase inhibitor, clade B, member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB

Cat:

SL0792R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human Maspin

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The Maspin protein is a sour depressant of nenzyme of a kind of silk ammonia that represses the tumor, is the sour depressant of protei nenzyme one member within super household of the silk ammonia, it is in repress the tumor growth and transfer exertive certain function.

Function:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Subunit:
Interacts with IRF6.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Normal mammary epithelial cells.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

Database links:

Entrez Gene: 5268 Human

Entrez Gene: 20724 Mouse

Entrez Gene: 116589 Rat

Omim: 154790 Human

SwissProt: P36952 Human

SwissProt: P70124 Mouse

SwissProt: P70564 Rat

Unigene: 55279 Human

Unigene: 268618 Mouse

Unigene: 25752 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Maspin蛋白是一种抑制肿瘤的丝氨酸蛋白酶抑制剂, 是丝氨酸蛋白酶抑制剂超家族中的一员，它在抑制肿瘤生长和转移中发挥一定作用。

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