Rabbit Anti-LIF/FITC Conjugated antibody

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DIA; CDF; Cholinergic Differentiation Factor; D factor; differentiation inhibitory activity; Differentiation stimulating factor; Differentiation-stimulating factor; Emfilermin; HILDA; Human interleukin in DA cells; Leukemia inhibitory factor; LIF; LIF_HUM

Cat:

SL1058R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Dog,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human LIF

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

20kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The leukemia inhibitory factor- LIF is a kind of cell factor that has various living creature functions.It has the leukemia cell of inducement to divide, regulating the growth metabolism of the bone organization, maintaining the basic characteristic of the Embryonicstem celles and promoting the mankind build the blood stem cell to divide to propagate, promote the cholinergic neuron to divide, obstruct the fat cell to synthesize, stimulate the muscle cell growth, regulate the liver cell to expect to respond the egg white to synthesize etc. in the acute the biology activity etc. function.

Function:
LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Subcellular Location:
Secreted.

Similarity:
Belongs to the LIF/OSM family.

Database links:

Entrez Gene: 3976 Human

Entrez Gene: 16878 Mouse

Omim: 159540 Human

SwissProt: P15018 Human

SwissProt: P09056 Mouse

Unigene: 2250 Human

Unigene: 4964 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生长因子和激素（ Growth Factor and Hormones）
白血病抑制因子-LIF是一种具有多种生物功能的细胞因子。它具有诱导白血病细胞分化，调节骨组织的生长代谢，维持胚胎干细胞（Embryonicstem celles细胞）的基本特征、促进人类造血干细胞的分化增殖、促进胆碱能神经元的分化、阻碍脂肪细胞合成、刺激成肌细胞生长、调节肝细胞中急性期反应蛋白的合成等生物学活性等作用.

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