background:
Cygb is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress.
Function:
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine.
Similarity:
Belongs to the globin family.
Database links:
Entrez Gene: 609341 Dog
Entrez Gene: 114757 Human
Entrez Gene: 114886 Mouse
Entrez Gene: 170520 Rat
Omim: 608759 Human
SwissProt: Q8WWM9 Human
SwissProt: Q9CX80 Mouse
SwissProt: Q921A4 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞球蛋白Cygb是最近发现的脊椎动物球蛋白超家族的一员,在体内分布广泛。 有学者认为:Cygb的确切功能尚不十分清楚,目前主要有携氧与储氧、氧感受器、活性氧基团和NO的清道夫、NADH氧化酶或过氧化氢酶样作用和参与胶原形成等假说。
|
|