Rabbit Anti-Chromogranin B/FITC Conjugated antibody

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Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.

Cat:

SL0543R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human CGB

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

72kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].

Function:
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Subcellular Location:
Secreted. Note=Neuroendocrine and endocrine secretory granules.

Tissue Specificity:
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.

Post-translational modifications:
Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.
O-glycosylated.

Similarity:
Belongs to the chromogranin/secretogranin protein family.

Database links:

Entrez Gene: 1114 Human

Entrez Gene: 12653 Mouse

Entrez Gene: 24259 Rat

Omim: 118920 Human

SwissProt: P05060 Human

SwissProt: P16014 Mouse

SwissProt: O35314 Rat

Unigene: 516874 Human

Unigene: 11090 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

嗜铬粒素B在肾上腺垂体胸腺子宫卵巢等神经内分泌组织表达该蛋白成分较多。

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