Rabbit Anti-ARC/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-ARC/FITC Conjugated antibody

ARG3.1; Arc; Arg 3.1; Activity regulated cytoskeletal associated protein; Activity regulated cytoskeletal protein; Activity-regulated cytoskeleton-associated protein; Activity regulated cytoskeletal-associated protein; ARC/ARG3.1; Activity-regulated gene

Cat:

SL0385R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ARC

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Activity-regulated cytoskeleton-associated protein (ARC)in the brain and learning and memory, researchers believe: ARC protein is by strengthening the function of synaptic links in order to save the memory, including learning and memory and emotion. At present, the scientists will also Activity-regulated cytoskeleton-associated protein used to take drugs addiction.

Function:
Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.

Subunit:
Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.

Subcellular Location:
Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse.

Similarity:
Belongs to the ARC/ARG3.1 family.

Database links:

Entrez Gene: 23237 Human

Entrez Gene: 11838 Mouse

Entrez Gene: 54323 Rat

Omim: 605235 Human

SwissProt: Q7LC44 Human

SwissProt: Q9WV31 Mouse

SwissProt: Q63053 Rat

Unigene: 40888 Human

Unigene: 741621 Human

Unigene: 25405 Mouse

Unigene: 10086 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

该蛋白与大脑的学习记忆有关，研究人员认为：是ARC蛋白通过加强了突触的联系功能从而储存了这些记忆，包括情感和学习记忆。
目前，科学家也将该蛋白用于吸食毒品成瘾性的研究。

Product Feedback Wall