Rabbit Anti-GATAD1/FITC Conjugated antibody

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ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUM

Cat:

SL11921R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human GATAD1/ODAG

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

29kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Function:
ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.

Subunit:
Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY.

Subcellular Location:
Nuclear

Tissue Specificity:
Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes.

DISEASE:
Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Similarity:
Contains 1 GATA-type zinc finger.

Database links:

Entrez Gene: 57798 Human

Entrez Gene: 67210 Mouse

SwissProt: Q8N5Y5 Human

SwissProt: Q8WUU5 Human

SwissProt: Q3TS14 Mouse

SwissProt: Q8VCQ2 Mouse

SwissProt: Q920S3 Mouse

SwissProt: Q9CSG2 Mouse

Unigene: 21145 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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