background:
Calcitonin receptor like receptor activity modifying protein 3; CRLR activity modifying protein 3; CRLR activity-modifying protein 3; OTTHUMP00000159549; OTTHUMP00000214279; OTTHUMP00000214280; Receptor (calcitonin) activity modifying protein 3; Receptor (G protein-coupled) activity modifying protein 3; Receptor activity modifying protein 3.
Function:
RAMP3 (receptor calcitonin activity modifying protein 3) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. It acts as a receptor for adrenomedullin (AM) together with CALCRL. It is strongly expressed in lung, breast, immune system and fetal tissues and belongs to the RAMP family.
Subunit:
Heterodimer of CALCRL and RAMP3
Subcellular Location:
Cell Membrane; Single-pass type I membrane protein
Tissue Specificity:
Strongly expressed in lung, breast, immune system and fetal tissues.
Similarity:
Belongs to the RAMP family.
Database links:
UniProtKB/Swiss-Prot: O60896.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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