Rabbit Anti-DNER/FITC Conjugated antibody

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Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.

Cat:

SL12115R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNER

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

75kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Subunit:
Interacts with AP1G1. Interacts with NOTCH1.

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

Database links:

Entrez Gene: 92737 Human

Entrez Gene: 227325 Mouse

Entrez Gene: 316573 Rat

Omim: 607299 Human

SwissProt: Q8NFT8 Human

SwissProt: Q8JZM4 Mouse

Unigene: 234074 Human

Unigene: 292560 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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