background:
DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types.
Subcellular Location:
Nuclear
Similarity:
Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:
Entrez Gene: 88097 Human
Entrez Gene: 223843 Mouse
Entrez Gene: 541457 Rat
SwissProt: Q6ZNG2 Human
Unigene: 302764 Human
Unigene: 152937 Mouse
Unigene: 93216 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|